Topical antibiotic therapy
Compared with systemic products, topical antibiotics usually have fewer side effects and permit a compliance-independent dosage of the medication. It is also possible to achieve considerably higher active ingredient concentrations in the place where they are needed. The following are considered as disadvantages: considerably more cumbersome to administer, higher costs and poor efficacy against organisms located outside the sulcus. In practice, the use of topical antibiotics is therefore especially recommended for the treatment of isolated defects and refractory residual pockets following a positive bacterial analysis.
Example of a topical antibiotic: Ligosan® Slow Release (In some countries Ligosan® Slow Release is also registered and available as Adjusan®, Ligosan® or Ligoslo®. Manufacturer: Kulzer)
- Topical antibiotic for the adjunctive treatment of chronic and aggressive periodontitis to supplement conventional, non-surgical standard treatment at pocket depths of > 5 mm
- After a single application, 14% doxycycline is released continuously from a biodegradable hydrogel matrix over a minimum period of 12 days
- Covers the relevant periodontopathogenic bacteria with additional anti-inflammatory activity